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Celiac disease: Causes, symptoms and treatments


Celiac disease, also called celiac sprue, is a condition that affects mostly the small intestine, although it can have consequences throughout the body. People with celiac disease experience digestive symptoms and potential long-term tissue damage as a result of the immune system attacking the inner lining of the small intestine (opens in new tab).

In nearly all cases, this immune reaction is triggered by the ingestion of gluten, a group of proteins present in grains such as wheat, rye and barley.

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